Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097380 | 1.00 | DPP4 (0.41) | DPP4PELI1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL6771363 | 0.89 | MAPK1 (0.40) | DPP4MAPK1KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL6771360 | 0.89 | MAPK1 (0.40) | DPP4MAPK1KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL6572196 | 0.83 | PELI1 (0.40) | PELI1MAPK1KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL6095315 | 0.82 | ENPP2 (0.45) | DPP4PELI1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL6095866 | 0.81 | PELI1 (0.40) | DPP4PELI1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL6095870 | 0.81 | PELI1 (0.40) | DPP4PELI1MAPK1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6095869 | 0.80 | PELI1 (0.39) | DPP4PELI1MAPK1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6095872 | 0.80 | PELI1 (0.39) | DPP4PELI1MAPK1KMT2AL3MBTL1 | |
| SCHEMBL6096936 | 0.77 | PELI1 (0.62) | PELI1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070626-B2 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | WELLA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | DPP4 3484/4885PELI1 1293/4885MAPK1 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.