Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138642 | 0.90 | MAPK1 (0.36) | KMT2AMAPK1L3MBTL1ENPP2PTGS2 | |
| Hydrochloric Acid SCHEMBL6139164 | 0.89 | MAPK1 (0.35) | KMT2AMAPK1L3MBTL1ENPP2PTGS2 | |
| SCHEMBL6097380 | 0.83 | DPP4 (0.41) | PELI1KMT2AMAPK1L3MBTL1ENPP2 | |
| SCHEMBL6097385 | 0.83 | DPP4 (0.41) | PELI1KMT2AMAPK1L3MBTL1ENPP2 | |
| SCHEMBL6573569 | 0.82 | PELI1 (0.40) | PELI1KMT2AMAPK1L3MBTL1ENPP2 | |
| Hydrochloric Acid SCHEMBL6570077 | 0.81 | PELI1 (0.39) | PELI1KMT2AMAPK1L3MBTL1ENPP2 | |
| SCHEMBL6095315 | 0.80 | ENPP2 (0.45) | PELI1KMT2AMAPK1L3MBTL1ENPP2 | |
| SCHEMBL6096936 | 0.74 | PELI1 (0.62) | PELI1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6096102 | 0.74 | PELI1 (0.47) | PELI1L3MBTL1ENPP2PTGS2ALDH1A1 | |
| SCHEMBL6096742 | 0.72 | PELI1 (0.48) | PELI1L3MBTL1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286953-B1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1286953-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002079144-A1 | (P-AMINO-HYDROXYPHENYL)-ACRYLAMIDE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |