Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 7/20 | 0.66 |
| ▸ | CDK2 | P24941 | 4/20 | 0.59 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097847 | 0.98 | KIFC1 (0.68) | KIFC1CDK2GPR34ITGB1ITGA4 | |
| SCHEMBL6098431 | 0.97 | KIFC1 (0.69) | KIFC1CDK2GPR34ITGB1ITGA4 | |
| SCHEMBL5927352 | 0.95 | KIFC1 (0.61) | KIFC1CDK2GPR34ITGB1ITGA4 | |
| SCHEMBL3972237 | 0.90 | KIFC1 (0.59) | KIFC1CDK2GPR34ITGB1ITGA4 | |
| SCHEMBL4824086 | 0.90 | KIFC1 (0.59) | KIFC1CDK2GPR34ITGB1ITGA4 | |
| SCHEMBL6100710 | 0.89 | KIFC1 (0.56) | KIFC1CDK2GPR34ITGB1ITGA4 | |
| SCHEMBL4831769 | 0.89 | CDK2 (0.60) | KIFC1CDK2GPR34MME | |
| SCHEMBL5927451 | 0.89 | CDK2 (0.60) | KIFC1CDK2GPR34MME | |
| SCHEMBL4831774 | 0.89 | CDK2 (0.60) | KIFC1CDK2GPR34MME | |
| SCHEMBL8337371 | 0.88 | KIFC1 (0.52) | KIFC1CDK2GPR34MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |