Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 7/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831950 | 0.91 | CDK2 (0.51) | KIFC1MMEITGB1ITGA4ITGB7 | |
| SCHEMBL5927352 | 0.90 | KIFC1 (0.61) | KIFC1MMEGPR34GPR132ITGB1 | |
| SCHEMBL6097762 | 0.89 | KIFC1 (0.66) | KIFC1MMEGPR34GPR132ITGB1 | |
| SCHEMBL5926438 | 0.88 | FPR2 (0.57) | KIFC1MMEGPR34GPR132ITGB1 | |
| SCHEMBL6100601 | 0.87 | ITGB1 (0.52) | KIFC1MMEGPR34GPR132ITGB1 | |
| SCHEMBL6097847 | 0.87 | KIFC1 (0.68) | KIFC1MMEGPR34ITGB1ITGA4 | |
| SCHEMBL6098431 | 0.86 | KIFC1 (0.69) | KIFC1MMEGPR34ITGB1ITGA4 | |
| SCHEMBL6100717 | 0.84 | MME (0.49) | MMESLC13A5 | |
| SCHEMBL6095738 | 0.83 | KIFC1 (0.52) | KIFC1MMEGPR34GPR132ITGB1 | |
| SCHEMBL5926411 | 0.82 | CDK2 (0.55) | KIFC1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |