Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443171 | 0.82 | CNR2 (0.45) | CYP2C9CYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6097834 | 0.78 | CNR2 (0.49) | CYP2C9CYP2C19CNR2POLBTAS2R14 | |
| SCHEMBL6096840 | 0.77 | CNR2 (0.48) | CYP2C9CYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6096343 | 0.76 | POLB (0.46) | PTGS2CYP2C9GRIA2CYP2C19NPC1 | |
| SCHEMBL4444967 | 0.76 | CYP1A2 (0.53) | TP53CNR2TAS2R14CNR1 | |
| SCHEMBL6096869 | 0.75 | POLB (0.51) | PTGS2CYP2C9GRIA2CYP2C19NPC1 | |
| SCHEMBL6096215 | 0.75 | PTGS2 (0.54) | PTGS2CYP2C9PTGS1ALOX5PTGES | |
| SCHEMBL6096757 | 0.74 | POLB (0.52) | PTGS2CYP2C9GRIA2CYP2C19NPC1 | |
| SCHEMBL6833587 | 0.74 | CNR2 (0.44) | SMN1; SMN2MAPTTP53CNR2POLB | |
| SCHEMBL7014542 | 0.74 | CNR2 (0.68) | TP53CNR2POLBTAS2R14CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | disclosed |