Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rac-Dichlorprop SCHEMBL8138132 | 0.89 | HTT (0.56) | TDP1TSHRRAB9APPARGPPARD | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL1664092 | 0.88 | TDP1 (0.82) | TDP1TSHRRAB9APTGDR2L3MBTL1 | |
| SCHEMBL6098184 | 0.87 | TDP1 (0.55) | TDP1TSHRRAB9AALDH1A1L3MBTL1 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL9525998 | 0.85 | TDP1 (0.82) | TDP1TSHRRAB9APTGDR2ALDH1A1 | |
| SCHEMBL10381113 | 0.85 | RAB9A (0.70) | TDP1TSHRRAB9AFFAR1PTGDR2 | |
| SCHEMBL10382178 | 0.85 | RAB9A (0.70) | TDP1TSHRRAB9AFFAR1PTGDR2 | |
| SCHEMBL10381793 | 0.84 | RAB9A (0.72) | TDP1TSHRRAB9AFFAR1PTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 | 0.82 | TDP1 (1.00) | TDP1TSHRPPARDPTGDR2MAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 | 0.82 | TDP1 (1.00) | TDP1TSHRPPARDPTGDR2MAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 | 0.82 | TDP1 (1.00) | TDP1TSHRPPARDPTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7002020-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050004174-A1 | Antibacterial agents | GORDEEV MIKHAIL F (US) | 2005-01-06 | — | — | US | disclosed |
| US-6562844-B2 | Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-6531470-B1 | Antimicrobial compounds | PHARMACIA & UPJOHN COMPANY | 2003-03-11 | — | — | US | disclosed |
| US-6239152-B1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004174-A1 | Antibacterial agents | PAICS, OXA1L, PNKP | TDP1 1990/4885TSHR 4716/4885RAB9A 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.