Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL6098182 | 0.89 | TDP1 (0.68) | TDP1TSHRPPARGPPARDL3MBTL1 | |
| Rac-Dichlorprop SCHEMBL9487632 | 0.84 | HPGD (0.62) | HTTTDP1TSHRL3MBTL1MAPT | |
| Mecoprop SCHEMBL8853485 | 0.82 | TSHR (0.67) | HTTTSHRPPARGPPARDMAPT | |
| SCHEMBL6098184 | 0.80 | TDP1 (0.55) | TDP1TSHRL3MBTL1MAPTMEN1 | |
| Rac-Dichlorprop SCHEMBL4658768 | 0.80 | TSHR (0.69) | HTTTDP1TSHRPPARGPPARD | |
| SCHEMBL2712703 | 0.79 | PPARA (0.55) | PPARGFFAR1PPARA | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL1664092 | 0.79 | TDP1 (0.82) | HTTTDP1TSHRL3MBTL1MAPT | |
| Rac-Dichlorprop SCHEMBL4658776 | 0.79 | TDP1 (0.60) | HTTTDP1TSHRPPARDMAPT | |
| Mcpb SCHEMBL8584416 | 0.78 | TSHR (0.66) | HTTTSHRMAPTMEN1KMT2A | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL9525998 | 0.76 | TDP1 (0.82) | TDP1TSHRL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |