Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.76 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | CTSA | P10619 | 3/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926427 | 0.88 | SCN9A (0.65) | SUCNR1SCN9ACTSACNR2 | |
| SCHEMBL5926357 | 0.87 | CTSA (0.62) | SUCNR1SCN9AFPR2CTSAITGB1 | |
| SCHEMBL26263285 | 0.87 | SUCNR1 (0.81) | SUCNR1SCN9ASCN10AABL1CTSA | |
| SCHEMBL26264461 | 0.87 | SUCNR1 (1.00) | SUCNR1SCN9ASCN10AABL1CTSA | |
| SCHEMBL6098309 | 0.83 | SUCNR1 (0.75) | SUCNR1CTSA | |
| SCHEMBL5927093 | 0.83 | SCN9A (0.54) | SUCNR1SCN9ACTSACNR2 | |
| SCHEMBL3995770 | 0.83 | FPR2 (0.63) | SUCNR1FPR2GPR132ITGB1ITGA4 | |
| SCHEMBL5927050 | 0.82 | CNR2 (0.53) | SUCNR1SCN9ACTSACNR2 | |
| SCHEMBL4831843 | 0.80 | FPR2 (0.56) | SUCNR1FPR2GPR132 | |
| SCHEMBL5926441 | 0.80 | ITGB1 (0.51) | SUCNR1SCN9ACTSAITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |