SCHEMBL26263285

SCHEMBL26263285

CC[C@H](NC(=O)c1cccc(-c2ccc(OC(F)(F)F)cc2)n1)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 6/20 0.81
SCN10A Q9Y5Y9 1/20 0.59
ABL1 P00519 1/20 0.52
SCN9A Q15858 7/20 0.52
CNR2 P34972 2/20 0.49
PDE2A O00408 1/20 0.48
AHR P35869 1/20 0.48
CNR1 P21554 1/20 0.47
CTSA P10619 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26264461 0.89 SUCNR1 (1.00) SUCNR1SCN10AABL1SCN9ACTSA
SCHEMBL26263291 0.88 SUCNR1 (0.63) SUCNR1SCN9ACNR2CNR1CTSA
SCHEMBL26263279 0.87 SUCNR1 (0.61) SUCNR1SCN9ACNR2CTSA
SCHEMBL6098304 0.87 SUCNR1 (0.76) SUCNR1SCN10AABL1SCN9ACNR2
SCHEMBL26263580 0.86 SUCNR1 (0.60) SUCNR1SCN9ACNR2CTSA
SCHEMBL26263268 0.84 SCN9A (0.60) SUCNR1SCN9ACNR2CNR1CTSA
SCHEMBL26263294 0.84 SUCNR1 (0.60) SUCNR1SCN9ACNR2CTSA
SCHEMBL25003803 0.81 SUCNR1 (0.67) SUCNR1SCN10AABL1SCN9A
SCHEMBL6098309 0.80 SUCNR1 (0.75) SUCNR1CTSA
SCHEMBL26263281 0.79 SUCNR1 (0.52) SUCNR1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885SCN10A 751/4885ABL1 4604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.