SCHEMBL6098447

SCHEMBL6098447

Cc1cc(C)c(N2C=[N+](c3c(C)cc(C)cc3C)CCC2)c(C)c1.F[B-](F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29603795 0.94 ALDH1A1 (0.34) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL29603410 0.92 ALDH1A1 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
Bromide SCHEMBL4539689 0.92 ALDH1A1 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL21722392 0.92 ALDH1A1 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL819057 0.91
SCHEMBL442095 0.84 ALDH1A1 (0.33) ALDH1A1POLBMAPTHTTSMN1; SMN2
Hydrochloric Acid SCHEMBL442699 0.82 ALDH1A1 (0.32) ALDH1A1POLBMAPTHTTSMN1; SMN2
Bromide SCHEMBL1608734 0.82 ALDH1A1 (0.32) ALDH1A1POLBMAPTHTTSMN1; SMN2
SCHEMBL18287206 0.80
SCHEMBL29602996 0.74 ALDH1A1 (0.34) ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084222-B2 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst ZEON CORPORATION (JP) 2006-08-01 US disclosed