Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442095 | 0.98 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| Bromide SCHEMBL1608734 | 0.96 | ALDH1A1 (0.32) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL819057 | 0.92 | — | — | |
| SCHEMBL18287206 | 0.90 | — | — | |
| SCHEMBL29603795 | 0.88 | ALDH1A1 (0.34) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17783834 | 0.86 | L3MBTL1 (0.30) | — | |
| Bromide SCHEMBL4539689 | 0.86 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL21722392 | 0.86 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL29603410 | 0.86 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1609624 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026535-B1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | INTERCOS ITALIANA (IT) | 2025-07-09 | — | — | EP | claimed |
| CN-114573531-B | Method for synthesizing FDCA through carbon dioxide oxidation and metal catalysis of HMF | 南京先进生物材料与过程装备研究院有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-114149467-B | Method for preparing ruthenium-carbene compounds | 成都西岭源药业有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-116217352-A | Method for preparing cannabigerol and analogues thereof | 上海中医药大学 | 2023-06-06 | — | — | CN | claimed |
| EP-3452009-B1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | INTERCOS ITALIANA (IT) | 2022-12-07 | — | — | EP | claimed |
| EP-4026535-A1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | Intercos S.p.A. (IT) | 2022-07-13 | — | — | EP | claimed |
| CN-114573531-A | Method for synthesizing FDCA through carbon dioxide oxidation and metal catalysis HMF | 南京先进生物材料与过程装备研究院有限公司 | 2022-06-03 | — | — | CN | claimed |
| US-10940106-B2 | Biodegradable copolymers for cosmetic use | INTERCOS S.P.A. (IT) | 2021-03-09 | — | — | US | claimed |
| US-20190159999-A1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | INTERCOS S.P.A. (IT) | 2019-05-30 | — | — | US | claimed |
| EP-3452009-A1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | Intercos S.p.A. (IT) | 2019-03-13 | — | — | EP | claimed |
| US-10053426-B2 | Process for the synthesis of metyrapone and alkylated metyrapone analogs | ALBEMARLE CORPORATION (US) | 2018-08-21 | — | — | US | claimed |
| US-20170334854-A1 | One-Step Process For The Synthesis Of Alkylated Metyrapone Analogs | W. R. GRACE & CO.-CONN. | 2017-11-23 | — | — | US | claimed |
| WO-2017191603-A1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | INTERCOS S.P.A. (IT) | 2017-11-09 | — | — | WO | claimed |
| EP-3237383-A1 | ONE-STEP PROCESS FOR THE SYNTHESIS OF ALKYLATED METYRAPONE ANALOGS | Albemarle Corporation (US) | 2017-11-01 | — | — | EP | claimed |
| WO-2016105619-A1 | ONE-STEP PROCESS FOR THE SYNTHESIS OF ALKYLATED METYRAPONE ANALOGS | ALBEMARLE CORPORATION (US) | 2016-06-30 | — | — | WO | claimed |
| WO-2010010559-A1 | CONTROLLED HYDROGEN GENERATION, STORAGE AND TRANSPORTATION SOLUTION | M.I.H.G. LTD. (IL) | 2010-01-28 | — | — | WO | claimed |
| US-20100021376-A1 | CONTROLLED HYDROGEN GENERATION, STORAGE AND TRANSPORTATION SOLUTION | SILBERMAN ALEX | 2010-01-28 | — | — | US | claimed |
| EP-4739672-A1 | NEW COMPOUNDS | Aston University (GB) | 2026-05-13 | — | — | EP | disclosed |
| US-6316380-B1 | ONE TRANSITION METAL COMPOUND AND AT LEAST ONE N-HETEROCYCLIC CARBENE OR ITS PROTONATED SALT | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2001-11-13 | — | — | US | disclosed |
| WO-2001066248-A2 | C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE | UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10940106-B2 | Biodegradable copolymers for cosmetic use | LAGE3, LMTK2, LSS | ALDH1A1 4234/4885POLB 1231/4885MAPT 2423/4885 |
| US-20190159999-A1 | BIODEGRADABLE COPOLYMERS FOR COSMETIC USE | LAGE3, LMTK2, LSS | ALDH1A1 4234/4885POLB 1231/4885MAPT 2423/4885 |
| US-20170334854-A1 | One-Step Process For The Synthesis Of Alkylated Metyrapone Analogs | MET, MEP1B, ABL1 | ALDH1A1 606/4885POLB 719/4885MAPT 3413/4885 |
| US-10053426-B2 | Process for the synthesis of metyrapone and alkylated metyrapone analogs | MET, ABL1, CMPK1 | ALDH1A1 872/4885POLB 911/4885MAPT 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.