SCHEMBL6098736

SCHEMBL6098736

NC(=O)C(c1ccccc1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
DHODH Q02127 1/20 0.45
KMO O15229 1/20 0.44
CTSD P07339 1/20 0.44
IKBKB O14920 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MGLL Q99685 1/20 0.42
CTSA P10619 1/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL741751 0.84 MEN1 (0.58) MEN1KMT2ACTSDTDP1L3MBTL1
SCHEMBL3585061 0.82 RXRA (0.51) RXRARXRBRXRGKMOMGLL
Hydrochloric Acid SCHEMBL8550499 0.82 MEN1 (0.56) MEN1KMT2ACTSDTDP1L3MBTL1
SCHEMBL19555119 0.81 ALDH1A1 (0.50) RXRARXRBRXRGDHODHCTSA
SCHEMBL27480602 0.80 RXRA (0.54) RXRARXRBRXRG
SCHEMBL30353435 0.80 RXRA (0.54) RXRARXRBRXRG
SCHEMBL6213432 0.80 RXRA (0.46) RXRARXRBRXRGDHODHKMO
SCHEMBL14894543 0.79 RXRA (0.53) RXRARXRBRXRGKMOMGLL
SCHEMBL2870552 0.79 HDAC4 (0.72) RXRARXRBRXRGMEN1KMT2A
Acetic Acid SCHEMBL9853044 0.78 MEN1 (0.53) MEN1KMT2ACTSDTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084176-B2 N-arylphenylacetamide derivatives and medicinal compositions containing the same DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 2006-08-01 US disclosed