Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189202 | 0.91 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL4183855 | 0.91 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL4194191 | 0.91 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL4183519 | 0.89 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL4183522 | 0.89 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL4183524 | 0.89 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL4196724 | 0.89 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL4183974 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL4183980 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL4196639 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001895-B2 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LABORATORIES (US) | 2006-02-21 | — | — | US | disclosed |
| US-20030225276-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225276-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | PTGS2 3/4885PTGS1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.