Hydrochloric Acid

Hydrochloric Acid

SCHEMBL609949

CC=[Zr+2](C1C(C)=Cc2c(-c3ccccc3)cccc21)C1C(C)=Cc2c(-c3ccccc3)cccc21.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5351713 0.85 BRD4 (0.31)
Hydrochloric Acid SCHEMBL218745 0.82 PDCD1 (0.33) PDCD1CD274CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL5169306 0.82 PDCD1 (0.33) PDCD1CD274CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL6065118 0.82 CHRNB2 (0.31) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL1024950 0.81
Hydrochloric Acid SCHEMBL1024948 0.81
Hydrochloric Acid SCHEMBL30525923 0.81 PDCD1 (0.32) PDCD1CD274CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL966562 0.80 PDCD1 (0.31) PDCD1CD274CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL5950948 0.80 PDCD1 (0.31) PDCD1CD274CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL338921 0.80 PDCD1 (0.31) PDCD1CD274CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2380918-B1 PROCESS FOR PRODUCING ALPHA-OLEFIN POLYMER, ALPHA-OLEFIN POLYMER, AND LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2019-07-24 EP disclosed
US-9023960-B2 Process for producing α-olefin polymer, α-olefin polymer, and lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2015-05-05 US disclosed
US-20120040878-A1 PROCESS FOR PRODUCING ALPHA-OLEFIN POLYMER, ALPHA-OLEFIN POLYMER, AND LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2012-02-16 US disclosed
EP-2380918-A1 PROCESS FOR PRODUCING a-OLEFIN POLYMER, a-OLEFIN POLYMER, AND LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2011-10-26 EP disclosed