SCHEMBL60997

SCHEMBL60997

Cc1ccc(C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ACHE P22303 2/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
CFTR P13569 1/20 0.44
GOPC Q9HD26 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 1/20 0.44
CHRNA7 P36544 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
GAA P10253 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3657920 1.00 LMNA (0.53) LMNAACHETSHRALOX12SLC6A2
Methane SCHEMBL11860709 0.97 LMNA (0.50) LMNAACHETSHRALOX12SLC6A2
SCHEMBL10452706 0.89 CYP19A1 (0.50) LMNAACHETSHRALOX12SLC6A2
SCHEMBL122911 0.88 ACHE (0.57) LMNAACHETSHRALOX12MAPT
SCHEMBL4989486 0.87 LMNA (0.41) LMNAACHETSHRALOX12SLC6A2
SCHEMBL12743903 0.87 CYP2C19 (0.42) LMNAACHETSHRALOX12SLC6A2
SCHEMBL261912 0.87 CYP2C19 (0.42) LMNAACHETSHRALOX12SLC6A2
SCHEMBL22566798 0.87 HTT (0.52) LMNATSHRSLC6A4MAPTTDP1
SCHEMBL29000147 0.85 LMNA (0.43) LMNAACHETSHRALOX12SLC6A2
SCHEMBL2956444 0.85 SLC6A2 (0.63) TSHRSLC6A2SLC6A4SLC6A3CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3112 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380998-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF Research Foundation Of The City University Of New York (US) 2024-06-12 EP claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
US-11884612-B2 Covalent peptide binders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-30 US claimed
US-20240025866-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS NOVARTIS AG (CH) 2024-01-25 US claimed
US-20240018099-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS NOVARTIS AG (CH) 2024-01-18 US claimed
US-20240010623-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS NOVARTIS AG (CH) 2024-01-11 US claimed
EP-4284444-A1 SOLID-PHASE SUPPORTED RADIOLABELING OF PEPTIDES University of Copenhagen (DK) 2023-12-06 EP claimed
US-11779653-B2 Multi-armed polyrotaxane platform for protected nucleic acid delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-10 US claimed
EP-3565573-B1 PAC1 RECEPTOR AGONISTS (MAXCAPS) AND USES THEREOF UNIV CALIFORNIA (US) 2023-08-23 EP claimed
CN-116438190-A Synthesis of Prostate Specific Membrane Antigen (PSMA) ligands 诺华股份有限公司 2023-07-14 CN claimed
US-5817811-A AMIDATION OF THE CORRESPOND ESTERIFIED AMINE COMPOUND WITH A CARBOXYLATED NUCLEOTIDE BASE HOECHST AKTIENGESELLSCHAFT (DE) 1998-10-06 US claimed
WO-1998037226-A1 COMPOSITIONS FOR THE DETECTION OF ENZYME ACTIVITY IN BIOLOGICAL SAMPLES AND METHODS OF USE THEREOF ONCOIMMUNIN, INC. (US) 1998-08-27 WO claimed
US-5721350-A Deuterated nucleosides CHATTOPADHYAYA JYOTI (SE) 1998-02-24 US claimed
EP-0672661-A1 Substituted N-ethyl-glycinderivatives for the preparation of PNA and PNA-/DNA hybrides HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-20 EP claimed
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 EP claimed
WO-1993025566-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA JYOTI (SE) 1993-12-23 WO claimed
US-4668777-A POLYNUCLEOTIDE INTERMEDIATES UNIVERSITY PATENTS, INC. (US) 1987-05-26 US claimed
EP-0061746-B1 PHOSPHORAMIDITE COMPOUNDS AND THEIR USE IN PRODUCING OLIGONUCLEOTIDES UNIVERSITY PATENTS, INC. (US) 1985-03-20 EP claimed
EP-0061746-A1 Phosphoramidite compounds and their use in producing oligonucleotides UNIVERSITY PATENTS, INC. (US) 1982-10-06 EP claimed
US-4181328-A Recording element FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US claimed