Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009386 | 1.00 | EPHX2 (0.44) | EPHX2KCNA5KCNH2NAPRTNFE2L2 | |
| Formic Acid SCHEMBL28304339 | 0.88 | NAPRT (0.43) | EPHX2KCNA5KCNH2NAPRTNFE2L2 | |
| SCHEMBL10354468 | 0.82 | NAPRT (0.39) | EPHX2KCNA5KCNH2NAPRTNFE2L2 | |
| SCHEMBL16472118 | 0.79 | NAPRT (0.41) | KCNA5KCNH2NAPRTALDH1A1TDP1 | |
| SCHEMBL8778835 | 0.79 | NAPRT (0.41) | EPHX2KCNA5KCNH2NAPRTNFE2L2 | |
| SCHEMBL2616434 | 0.79 | NAPRT (0.41) | KCNA5KCNH2NAPRTALDH1A1TDP1 | |
| SCHEMBL15624412 | 0.78 | TRPV1 (0.47) | EPHX2TRPV1 | |
| SCHEMBL31608519 | 0.76 | EPHX2 (0.44) | EPHX2NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL8436654 | 0.76 | EPHX2 (0.44) | EPHX2NFE2L2ALDH1A1MAPTATM | |
| SCHEMBL646416 | 0.76 | NAPRT (0.42) | KCNA5KCNH2NAPRTALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114361590-B | Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery | 松山湖材料实验室 | 2023-07-25 | — | — | CN | claimed |
| CN-113788784-B | Preparation method of 2-fluoro-3-trifluoromethyl pyridine | 山东省农药科学研究院 | 2023-06-13 | — | — | CN | claimed |
| CN-114361590-A | Lithium ion battery electrolyte additive, electrolyte and lithium ion battery | 松山湖材料实验室 | 2022-04-15 | — | — | CN | claimed |
| CN-113788784-A | Preparation method of 2-fluoro-3-trifluoromethylpyridine | 山东省农药科学研究院 | 2021-12-14 | — | — | CN | claimed |
| EP-0204535-B1 | N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-08-19 | — | — | EP | claimed |
| US-20260137680-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LTD (GB) | 2026-05-21 | — | — | US | disclosed |
| EP-3558298-B1 | ANTIDIABETIC SPIROCHROMAN COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20250276967-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | SIGNAL PHARMACEUTICALS, LLC | 2025-09-04 | — | — | US | disclosed |
| US-12338235-B2 | Heterocyclic compounds and their use for treatment of helminthic infections and diseases | CELGENE CORPORATION (US) | 2025-06-24 | — | — | US | disclosed |
| CN-119968366-A | Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases | 西特瑞治疗有限公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| US-20250049772-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-02-13 | — | — | US | disclosed |
| EP-0494770-A1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT COMPANY, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4996320-A | Thyroid inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0110690-B1 | PREPARATION OF (TRIFLUOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0204535-A1 | N-fluoropyridinium salt and process for preparing same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-10 | — | — | EP | disclosed |
| US-4590279-A | CATALYTIC FLUORINATION OF (TRICHLOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0110690-A1 | Preparation of (trifluoromethyl)pyridines | THE DOW CHEMICAL COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4125618-A | Novel substituted pyridines, their preparation and pharmaceutical use | MERCK & CO., INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4060601-A | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260137680-A1 | NOVEL COMPOUNDS | CCR1, CCR4, CCR3 | EPHX2 789/4885KCNA5 1474/4885KCNH2 882/4885 |
| US-20250276967-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CYP8B1, HAX1, HRH4 | EPHX2 123/4885KCNA5 3646/4885KCNH2 3619/4885 |
| US-20250049772-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | SSTR4, SSTR3, NPY4R | EPHX2 3811/4885KCNA5 2382/4885KCNH2 2036/4885 |
| US-12338235-B2 | Heterocyclic compounds and their use for treatment of helminthic infections and diseases | CYP8B1, HAX1, HRH4 | EPHX2 123/4885KCNA5 3646/4885KCNH2 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.