SCHEMBL6100263

SCHEMBL6100263

COc1cccc2ccc(O)cc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.53
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
TRPV1 Q8NER1 1/20 0.49
NQO1 P15559 1/20 0.48
MAOB P27338 1/20 0.48
GFER P55789 1/20 0.47
FLT3 P36888 2/20 0.47
RXRA P19793 1/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
EIF4H Q15056 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16034165 0.87 MAOA (0.48) MCL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30203238 0.85 KDM4E (0.51) KDM4EALDH1A1HPGDHSD17B10NQO1
SCHEMBL3163561 0.85 KDM4E (0.51) KDM4EALDH1A1HPGDHSD17B10NQO1
SCHEMBL8466040 0.84 MCL1 (0.52) MCL1KDM4EALDH1A1HSD17B10TRPV1
SCHEMBL15423101 0.81 MEN1 (0.48) MCL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29090123 0.81 GFER (0.51) MCL1TRPV1GFERRXRAPPARG
SCHEMBL30547016 0.81 GFER (0.51) MCL1TRPV1GFERRXRAPPARG
Resorcinol SCHEMBL10357607 0.80 ESR1 (0.50) MCL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29919905 0.79 NQO1 (0.67) KDM4EALDH1A1HPGDHSD17B10NQO1
SCHEMBL8393507 0.79 NQO1 (0.67) KDM4EALDH1A1HPGDHSD17B10NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119073-A Novel fluorane compound and preparation method thereof 沈阳感光化工研究院有限公司 2024-12-13 CN claimed
CN-119119073-A Novel fluorane compound and preparation method thereof 沈阳感光化工研究院有限公司 2024-12-13 CN disclosed
CN-115536502-A Preparation method and application of 7-methoxy-1-naphthol 阜阳欣奕华制药科技有限公司 2022-12-30 CN disclosed
US-7001900-B2 Azabicyclic compounds for the treatment of disease PFIZER INC. (US) 2006-02-21 US disclosed
EP-1478646-A1 AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY PHARMACIA & UPJOHN COMPANY (US) 2004-11-24 EP disclosed
EP-0992524-B1 Process for preparing polyether polyols BAYER AG (DE) 2004-02-18 EP disclosed
US-20030236270-A1 Azabicyclic compounds for the treatment of disease PHARMACIA & UPJOHN COMPANY 2003-12-25 US disclosed
US-6624321-B2 Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate BAYER AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed
WO-2003072578-A1 AZABICYCLIC COMPOUNDS WITH ALFA7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY PHARMACIA & UPJOHN COMPANY (US) 2003-09-04 WO disclosed
US-20030097026-A1 Process for the preparation of polyether polyols DENNINGER UWE (DE) 2003-05-22 US disclosed
US-6492565-B2 USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST BAYER AKTIENGESELLSCHAFT (DE) 2002-12-10 US disclosed
US-20010053866-A1 Process for the preparation of polyether polyols BAYER AKTIENGESELLSCHAFT (DE) 2001-12-20 US disclosed
EP-0992524-A2 Process for preparing polyether polyols BAYER AG (DE) 2000-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030097026-A1 Process for the preparation of polyether polyols PCBP1, FHIT, PUF60 MCL1 510/4885KDM4E 1896/4885ALDH1A1 3594/4885
US-20030236270-A1 Azabicyclic compounds for the treatment of disease MALT1, TPMT, CYP2B6 MCL1 158/4885KDM4E 1589/4885ALDH1A1 698/4885
US-20010053866-A1 Process for the preparation of polyether polyols PCBP1, FHIT, PUF60 MCL1 510/4885KDM4E 1896/4885ALDH1A1 3594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.