Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815561 | 0.89 | BIRC2 (0.40) | HSD17B10BIRC2ITGB3ITGB2ITGB1 | |
| SCHEMBL31679369 | 0.88 | CXCR4 (0.42) | HSD17B10BIRC2ITGB3ITGB2ITGB1 | |
| SCHEMBL2781615 | 0.86 | HSD17B10 (0.36) | HSD17B10ITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL6100284 | 0.85 | BIRC2 (0.41) | HSD17B10BIRC2ITGB3ITGB2ITGB1 | |
| SCHEMBL15894887 | 0.82 | BIRC2 (0.38) | HSD17B10BIRC2ITGB3ITGB2ITGB1 | |
| SCHEMBL24296905 | 0.79 | BIRC2 (0.36) | HSD17B10BIRC2SIGMAR1 | |
| SCHEMBL19798127 | 0.77 | HSD17B10 (0.41) | HSD17B10ITGB3ITGA2BSIGMAR1SLC6A9 | |
| SCHEMBL9187015 | 0.76 | BIRC2 (0.40) | HSD17B10BIRC2SIGMAR1 | |
| SCHEMBL2914157 | 0.74 | TSHR (0.38) | BIRC2ITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL454245 | 0.74 | HSD17B10 (0.56) | HSD17B10ITGB3ITGA2BSIGMAR1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040022857-A1 | Synthesis of highly conjugated polymers | GENERAL ELECTRIC COMPANY | 2004-02-05 | — | — | US | claimed |