Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.45 |
| ▸ | CTSA | P10619 | 7/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926193 | 0.91 | P2RX1 (0.43) | MMP12MMEP2RX1DCAF1CTSA | |
| SCHEMBL4827815 | 0.89 | DCAF1 (0.54) | MMP12DCAF1CTSASUCNR1 | |
| SCHEMBL6100717 | 0.88 | MME (0.49) | MMP12MMECTSAITGB3ITGAV | |
| SCHEMBL5927615 | 0.88 | CTSA (0.47) | MMEP2RX1DCAF1CTSASUCNR1 | |
| SCHEMBL6098336 | 0.86 | MMP12 (0.60) | MMP12MMECTSASUCNR1ITGB3 | |
| SCHEMBL6100601 | 0.86 | ITGB1 (0.52) | MMEP2RX1DHODHTHRATHRB | |
| SCHEMBL3989530 | 0.85 | CTSA (0.48) | P2RX1DCAF1CTSAFFAR1 | |
| SCHEMBL6097139 | 0.85 | CTSA (0.48) | P2RX1DCAF1CTSAFFAR1 | |
| SCHEMBL4824692 | 0.83 | MME (0.46) | MMEP2RX1DHODHTHRATHRB | |
| SCHEMBL4824688 | 0.83 | MME (0.46) | MMEP2RX1DHODHTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |