SCHEMBL610064

SCHEMBL610064

CCN(CC)c1ccc(C(C)=S)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
GAA P10253 4/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
POLB P06746 2/20 0.51
NOX1 Q9Y5S8 2/20 0.51
MCL1 Q07820 1/20 0.51
ALDH1A1 P00352 9/20 0.50
MAPK1 P28482 3/20 0.50
TSHR P16473 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611209 0.84 ALDH1A1 (0.52) MAPTGAAMEN1KMT2APOLB
SCHEMBL4303253 0.81 SMN1; SMN2 (0.55) MAPTGAAMEN1KMT2APOLB
SCHEMBL9915626 0.79 ALDH1A1 (0.56) MAPTGAAMEN1KMT2APOLB
SCHEMBL611731 0.78 MAPT (0.51) MAPTGAAMEN1KMT2APOLB
SCHEMBL181431 0.78 MAPT (0.77) MAPTGAAMEN1KMT2APOLB
SCHEMBL11698082 0.78 MAPT (0.51) MAPTGAAMEN1KMT2APOLB
SCHEMBL1735497 0.78 ALDH1A1 (0.74) MAPTGAAMEN1KMT2ANOX1
SCHEMBL610430 0.78 TDP1 (0.53) MAPTGAAMEN1KMT2APOLB
SCHEMBL9057697 0.76 TDP1 (0.51) MAPTGAAMEN1KMT2APOLB
SCHEMBL301479 0.76 TDP1 (0.51) MAPTGAAMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
CN-104334629-A Tread rubber composition and pneumatic tire SUMITOMO RUBBER IND 2015-02-04 CN disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
CN-102382258-A Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO 2012-03-21 CN disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed