SCHEMBL610430

SCHEMBL610430

CCN(CC)c1ccc(C(=S)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.53
HDAC6 Q9UBN7 2/20 0.53
CNR2 P34972 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NOX1 Q9Y5S8 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
HSD11B1 P28845 1/20 0.50
ESRRG P62508 1/20 0.47
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611209 0.92 ALDH1A1 (0.52) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL301479 0.87 TDP1 (0.51) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL9057697 0.87 TDP1 (0.51) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL609848 0.84 ALDH1A1 (0.53) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL14982110 0.81 RAB9A (0.63) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL609137 0.81 MEN1 (0.63) TDP1HDAC6CNR2MEN1KMT2A
Benzophenone SCHEMBL10489584 0.81 HPGD (0.63) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL8927062 0.81 HSD11B1 (0.54) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL51623 0.81 HPGD (0.63) TDP1HDAC6CNR2MEN1KMT2A
SCHEMBL8579335 0.79 TDP1 (0.51) TDP1HDAC6CNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
CN-104334629-A Tread rubber composition and pneumatic tire SUMITOMO RUBBER IND 2015-02-04 CN disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed