Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187811 | 1.00 | TSHR (0.41) | TSHRALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL19248428 | 0.83 | TSHR (0.41) | TSHRALDH1A1SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL16086739 | 0.83 | TSHR (0.43) | TSHRALDH1A1SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL27960965 | 0.83 | TSHR (0.43) | TSHRALDH1A1SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL27960966 | 0.83 | TSHR (0.43) | TSHRALDH1A1SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL24924115 | 0.82 | TSHR (0.39) | TSHRALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL24950471 | 0.82 | TSHR (0.39) | TSHRALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL677268 | 0.80 | TSHR (0.38) | TSHRALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL25128372 | 0.80 | GABRP (0.52) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21663697 | 0.80 | ALOX15 (0.50) | TSHRALDH1A1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4414451-A2 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4 HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | Genomatica, Inc. (US) | 2024-08-14 | — | — | EP | disclosed |
| EP-2989113-B1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11932845-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230065295-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2023-03-02 | — | — | US | disclosed |
| EP-4056706-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | Genomatica, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| US-11401534-B2 | Microorganisms for the production of 1,4- butanediol and related methods | GENOMATICA, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| EP-3392340-B1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA INC (US) | 2022-01-05 | — | — | EP | disclosed |
| CN-113528417-A | Microorganisms for producing 1, 4-butanediol and related methods | 基因组股份公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-107384846-B | Microorganisms for producing 1, 4-butanediol and related methods | 基因组股份公司 | 2021-08-10 | — | — | CN | disclosed |
| US-11085015-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20130071886-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130034884-A1 | MICROORGANISMS FOR PRODUCING 1,4-BUTANEDIOL AND METHODS RELATED THERETO | GENOMATICA, INC. (US) | 2013-02-07 | — | — | US | disclosed |
| US-20130029381-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO | GENOMATICA, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-20120225463-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-8129156-B2 | Microorganisms for the production of 1,4-butanediol | GENOMATICA, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129169-B2 | Microorganisms for the production of 1,4-butanediol and related methods | GENOMATICA, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110159572-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | GENOMATICA, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110045575-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | GENOMATICA, INC. | 2011-02-24 | — | — | US | disclosed |
| US-7858350-B2 | Microorganisms for the production of 1,4-butanediol | GENOMATICA, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100112654-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | AGAIN BIO APS (DK) | 2010-05-06 | — | — | US | disclosed |