Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438746 | 0.97 | CA1 (0.60) | CA1CA2IDO1AGXTTSHR | |
| SCHEMBL8082823 | 0.88 | CA1 (0.70) | CA1CA2IDO1AGXTTBXAS1 | |
| SCHEMBL19660911 | 0.86 | CA1 (0.59) | CA1CA2IDO1AGXTTSHR | |
| SCHEMBL1194332 | 0.83 | CA1 (0.73) | CA1CA2IDO1AGXTTSHR | |
| SCHEMBL14538696 | 0.83 | CA1 (0.73) | CA1CA2IDO1AGXTTSHR | |
| SCHEMBL1194330 | 0.83 | CA1 (0.73) | CA1CA2IDO1AGXTTSHR | |
| SCHEMBL28428718 | 0.83 | CA1 (0.46) | CA1CA2TSHRCYP2C9KMT2A | |
| SCHEMBL28642198 | 0.82 | CA1 (0.43) | CA1CA2KMT2ATDP1L3MBTL1 | |
| SCHEMBL28570988 | 0.82 | TACR1 (0.44) | CA1CA2AGXTKMT2AALDH1A1 | |
| SCHEMBL15890495 | 0.82 | CA1 (0.55) | CA1CA2IDO1AGXTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| US-20060247222-A1 | Glycosidase inhibitors and methods of synthesizing same | SIMON FRASER UNIVERSITY (CA) | 2006-11-02 | — | — | US | disclosed |
| US-20050065139-A1 | Glycosidase inhibitors and methods of synthesizing same | MEDINNOVA PARTNERS INC. (CA) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247222-A1 | Glycosidase inhibitors and methods of synthesizing same | STS, SCLY, MGAM | CA1 148/4885CA2 216/4885IDO1 720/4885 |
| US-20050065139-A1 | Glycosidase inhibitors and methods of synthesizing same | STS, SCLY, MGAM | CA1 306/4885CA2 433/4885IDO1 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.