Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 7/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24634748 | 0.89 | CA1 (0.70) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL6101489 | 0.88 | CA1 (0.60) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL28438746 | 0.88 | CA1 (0.60) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL12859364 | 0.87 | CA1 (0.56) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL15831104 | 0.87 | CA1 (0.68) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL19660911 | 0.87 | CA1 (0.59) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL22602252 | 0.85 | L3MBTL1 (0.55) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL31506240 | 0.84 | CA1 (0.69) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL31506185 | 0.84 | CA1 (0.69) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL26985990 | 0.84 | CA1 (0.69) | CA1CA2IDO1AGXTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030733-A1 | METHOD FOR THE SYNTHESIS OF 4-ALKOXY-, 4-HYDROXY- AND 4-ARYLOXY-SUBSTITUTED TETRAHYDRO-FURO[3,4-B]FURAN-2(3H)-ONE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2009-03-12 | — | — | WO | disclosed |