⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449158 | 0.84 | GAA (0.40) | — | |
| SCHEMBL19271777 | 0.84 | POLB (0.32) | — | |
| SCHEMBL122141 | 0.82 | BRD4 (0.41) | — | |
| SCHEMBL868298 | 0.80 | MITF (0.40) | — | |
| SCHEMBL15561512 | 0.80 | POLB (0.33) | — | |
| SCHEMBL16281888 | 0.80 | MITF (0.40) | — | |
| SCHEMBL1625501 | 0.80 | MITF (0.40) | — | |
| SCHEMBL10814875 | 0.79 | — | — | |
| SCHEMBL19276513 | 0.79 | CHRNA7 (0.38) | — | |
| SCHEMBL19449177 | 0.77 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239828-A1 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-20230399355-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230399355-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230355791-A1 | GLYCAN-CONJUGATED ANTIBODIES BINDING TO FC-GAMMA RECEPTOR | SYNAFFIX B.V. (NL) | 2023-11-09 | — | — | US | disclosed |
| US-11795192-B2 | Antimicrobial compounds, compositions, and uses thereof | Lakewood Amedex, Inc. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11795192-B2 | Antimicrobial compounds, compositions, and uses thereof | Lakewood Amedex, Inc. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-5217839-A | Dispersion containing mixture of a polymer with a carbon nitrogen double bond and a colorant in a vinyl monomer | NIPPON ZEON CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| US-5216080-A | Butadiene-styrene copolymers endcapped with N-modified amino ketones, thioamino ketones, thioamino aldehydes, lactams, thiolactams, ethyleneurea and thioethylene urea; wear resistant, large-sized tires | NIPPON ZEON CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5155161-A | Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis | NIPPON ZEON CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0488346-A1 | Process for preparation of styrene resin composition and styrene resin composition | NIPPON ZEON CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0438248-A2 | Preparation process of toner | NIPPON ZEON CO., LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |
| EP-0435544-A2 | Abrasion-resistant rubber compositions | NIPPON ZEON CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0434353-A2 | Rubber compositions | NIPPON ZEON CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
| US-5001196-A | Process for preparation of diene type polymer rubber | NIPPON ZEON CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0382205-A2 | Additive for thermosetting resins and thermosetting resin composition containing additive | NIPPON ZEON CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4178286-A | β-Lactams, their production, intermediates thereto and derivatives thereof | RESEARCH CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |