Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.59 |
| ▸ | CTSL | P07711 | 8/20 | 0.59 |
| ▸ | CTSB | P07858 | 5/20 | 0.48 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107836 | 0.92 | CTSS (0.51) | CTSSCTSLCTSBCTSKMMP2 | |
| SCHEMBL6108723 | 0.88 | CTSL (0.60) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6108566 | 0.86 | CTSS (0.59) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6109161 | 0.86 | CTSS (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6108385 | 0.86 | CTSS (0.62) | CTSSCTSLCTSBCTSK | |
| SCHEMBL5359805 | 0.86 | CTSS (0.45) | CTSSCTSLCTSBCTSKMMP2 | |
| SCHEMBL5359796 | 0.86 | CTSS (0.45) | CTSSCTSLCTSBCTSKMMP2 | |
| SCHEMBL3903257 | 0.84 | CTSS (0.46) | CTSSCTSLMMP2MMP9MMP8 | |
| SCHEMBL7083037 | 0.80 | CTSL (0.43) | CTSSCTSLCTSBCTSKMMP2 | |
| SCHEMBL6106481 | 0.80 | CTSS (0.57) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982272-B2 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | disclosed |