Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610580 | 0.87 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL188296 | 0.87 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1018643 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14164778 | 0.78 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3279730 | 0.78 | KMT2A (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7742171 | 0.77 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2116862 | 0.77 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29851101 | 0.77 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL354228 | 0.74 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11435681 | 0.74 | MAPT (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857446-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9790359-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20150099823-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2015-04-09 | — | — | US | disclosed |
| EP-2857446-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-8334339-B2 | Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20120041134-A1 | CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |