Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188296 | 0.91 | MEN1 (0.65) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL14164778 | 0.82 | MEN1 (0.57) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL1018643 | 0.82 | ALDH1A1 (0.64) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL7742171 | 0.80 | MEN1 (0.55) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL29851101 | 0.80 | SMN1; SMN2 (0.55) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL2116862 | 0.80 | SMN1; SMN2 (0.55) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL610579 | 0.78 | MEN1 (0.53) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL3280428 | 0.78 | TP53 (0.50) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL2646528 | 0.77 | MEN1 (0.57) | KMT2AMEN1SMN1; SMN2KEAP1TP53 | |
| SCHEMBL354228 | 0.77 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2KEAP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700196-B2 | Method for producing carbonyl group-containing organosilicon compounds | WACKER CHEMIE AG (DE) | 2010-04-20 | — | — | US | disclosed |
| EP-1685183-B1 | METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-20070129520-A1 | High yield of 2-formylethyldimethylsilanol-modified polydimethylsiloxane obtained by the continuous process of oxidizing 3-hydroxypropyldimethylsilanol-modified corresponding polymer using Tempoas an oxidation catalyst and air or oxygen as oxidizer in an aqueous dispersion; industrial scale; low cost | WACKER CHEMIE AG (DE) | 2007-06-07 | — | — | US | disclosed |