Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.49 |
| ▸ | CTSK | P43235 | 9/20 | 0.49 |
| ▸ | CTSB | P07858 | 7/20 | 0.49 |
| ▸ | CTSL | P07711 | 11/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LONP1 | P36776 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108151 | 0.91 | CTSL (0.43) | CTSSCTSKCTSBCTSLCYP2D6 | |
| SCHEMBL6106304 | 0.84 | CTSS (0.61) | CTSSCTSKCTSBCTSLLONP1 | |
| SCHEMBL5368682 | 0.84 | CTSL (0.57) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6107017 | 0.83 | CTSL (0.49) | CTSSCTSKCTSBCTSLCYP2D6 | |
| SCHEMBL5363899 | 0.80 | CTSL (0.62) | CTSSCTSKCTSBCTSL | |
| SCHEMBL5366984 | 0.78 | CTSL (0.54) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6974052 | 0.77 | CTSL (0.40) | CTSSCTSKCTSBCTSL | |
| SCHEMBL5374916 | 0.77 | CTSL (0.50) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6108221 | 0.77 | CTSS (0.50) | CTSSCTSKCTSBCTSL | |
| SCHEMBL6107843 | 0.77 | CTSS (0.50) | CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982272-B2 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | disclosed |