Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 5/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | BLVRB | P30043 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109415 | 0.88 | XDH (0.36) | TARBP2XDHABCC4ABCB11PGR | |
| SCHEMBL5238512 | 0.87 | DPP4 (0.34) | DPP4PIK3CACYP2C9RXRA | |
| SCHEMBL6108065 | 0.85 | DPP4 (0.44) | DPP4 | |
| SCHEMBL6108230 | 0.85 | SHMT2 (0.36) | DPP4PIK3CAMEN1KMT2APPARA | |
| SCHEMBL5234400 | 0.84 | DPP4 (0.39) | TARBP2XDHABCC4ABCB11PGR | |
| SCHEMBL6107869 | 0.83 | DPP4 (0.40) | DPP4MEN1KMT2A | |
| SCHEMBL6109017 | 0.83 | HTT (0.32) | TARBP2XDHABCC4ABCB11PGR | |
| Hydrochloric Acid SCHEMBL5236389 | 0.83 | DPP4 (0.46) | TARBP2DPP4 | |
| SCHEMBL5234405 | 0.82 | TARBP2 (0.39) | TARBP2XDHABCC4ABCB11PGR | |
| SCHEMBL6107138 | 0.82 | DPP4 (0.37) | TARBP2XDHABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |