Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626219 | 0.79 | MAPT (0.42) | MAPTEGLN3CYP19A1LMNAHSP90AA1 | |
| SCHEMBL2106586 | 0.77 | MAPT (0.36) | MAPTEGLN3CYP19A1LMNACYP26A1 | |
| SCHEMBL5440264 | 0.75 | MAPT (0.49) | MAPTEGLN3CYP19A1LMNACYP26A1 | |
| SCHEMBL22365110 | 0.74 | CYP19A1 (0.36) | MAPTCYP19A1CYP26A1CYP3A4CYP1A2 | |
| SCHEMBL23666063 | 0.72 | FDPS (0.38) | KMT2AACHEMEN1 | |
| SCHEMBL10900677 | 0.70 | MAPT (0.44) | MAPTEGLN3CYP19A1LMNACYP3A4 | |
| SCHEMBL2754295 | 0.70 | MAPT (0.44) | MAPTEGLN3CYP19A1LMNACYP3A4 | |
| SCHEMBL9240844 | 0.70 | EGLN3 (0.38) | MAPTEGLN3CYP19A1LMNACYP26A1 | |
| SCHEMBL9240851 | 0.70 | EGLN3 (0.38) | MAPTEGLN3CYP19A1LMNACYP26A1 | |
| SCHEMBL20981285 | 0.70 | CYP19A1 (0.38) | MAPTCYP19A1CYP26A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037925-B2 | 4-anilinoquinoline-3-carboxamides | ASTRAZENECA AB (SE) | 2006-05-02 | — | — | US | disclosed |