Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.64 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879916 | 0.91 | SLC6A4 (0.69) | SLC6A4 | |
| SCHEMBL30468389 | 0.91 | SLC6A4 (0.69) | SLC6A4 | |
| SCHEMBL29499049 | 0.90 | SLC6A4 (0.67) | SLC6A4 | |
| SCHEMBL3082624 | 0.90 | SLC6A4 (0.67) | SLC6A4 | |
| SCHEMBL18011078 | 0.88 | SLC6A4 (0.66) | SLC6A4 | |
| SCHEMBL25244606 | 0.84 | SLC6A4 (0.64) | SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL8136598 | 0.84 | SLC6A4 (0.64) | SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL2531600 | 0.84 | SLC6A4 (0.64) | SLC6A4DRD3 | |
| SCHEMBL12881233 | 0.84 | SLC6A4 (0.68) | SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL27402888 | 0.84 | SLC6A4 (0.64) | SLC6A4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122191-A1 | N-(indolethyl-)cycloamine compounds | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | US | claimed |
| EP-1572646-A1 | N-(INDOLETHYL-)CACLOAMINE COMPOUNDS | MERCK PATENT GmbH (DE) | 2005-09-14 | — | — | EP | claimed |
| WO-2004054972-A1 | N-(INDOLETHYL-)CACLOAMINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2004-07-01 | — | — | WO | claimed |
| US-20060122191-A1 | N-(indolethyl-)cycloamine compounds | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | US | disclosed |
| EP-1572646-A1 | N-(INDOLETHYL-)CACLOAMINE COMPOUNDS | MERCK PATENT GmbH (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054972-A1 | N-(INDOLETHYL-)CACLOAMINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2004-07-01 | — | — | WO | disclosed |
| CN-1056610-C | Piperidines and piperazines | MERCK PATENT GMBH (DE) | 2000-09-20 | — | — | CN | disclosed |
| EP-0648767-B1 | Piperdine and piperazine derivatives which affect the C.N.S. | MERCK PATENT GMBH (DE) | 1997-05-28 | — | — | EP | disclosed |
| US-5532241-A | Piperidines and piperazines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| CN-1106811-A | Piperidines and piperazines | MERCK PATENG GES MIT BESCHRAEN (DE) | 1995-08-16 | — | — | CN | disclosed |
| EP-0648767-A1 | Piperdine and piperazine derivatives which affect the C.N.S. | MERCK PATENT GmbH (DE) | 1995-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122191-A1 | N-(indolethyl-)cycloamine compounds | HTR1A, HTR2A, HTR5A | SLC6A4 93/4885DRD2 59/4885DRD4 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.