Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607911 | 0.83 | NPC1 (0.48) | F10F2PLATKLKB1KMT2A | |
| SCHEMBL6108909 | 0.81 | F10 (0.47) | ALDH1A1F10BDKRB1LDHA | |
| SCHEMBL6717550 | 0.73 | F10 (0.45) | F10KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6108431 | 0.73 | F10 (0.45) | F10RAB9ANPC1 | |
| SCHEMBL6109172 | 0.72 | USP30 (0.45) | F10RAB9ANPC1 | |
| SCHEMBL6107816 | 0.72 | NPC1 (0.49) | F10BDKRB1KMT2AMEN1RAB9A | |
| SCHEMBL6107341 | 0.72 | F10 (0.43) | F10RAB9ANPC1 | |
| SCHEMBL7016107 | 0.71 | JAK2 (0.50) | F10F2PLATKLKB1LDHA | |
| Trifluoroacetic Acid SCHEMBL6108697 | 0.69 | F10 (0.45) | F10KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL784478 | 0.69 | ALDH1A1 (0.41) | ALDH1A1F10F2PLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129245-B2 | Anticoagulants which act selectively on factor Xa; fast acting; oral; do not interfere with lysis of blood clots | ELI LILLY AND COMPANY (US) | 2006-10-31 | — | — | US | disclosed |