Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | BDKRB1 | P46663 | 10/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607913 | 0.84 | F10 (0.47) | F10 | |
| SCHEMBL6108906 | 0.81 | ALDH1A1 (0.42) | F10BDKRB1LDHAALDH1A1 | |
| SCHEMBL6108432 | 0.73 | F10 (0.47) | F10 | |
| SCHEMBL6108348 | 0.73 | F10 (0.47) | F10 | |
| SCHEMBL6109175 | 0.72 | F10 (0.46) | F10 | |
| SCHEMBL6107819 | 0.72 | F10 (0.51) | F10BDKRB1 | |
| SCHEMBL6107346 | 0.72 | F10 (0.45) | F10 | |
| SCHEMBL6107862 | 0.71 | F10 (0.46) | F10 | |
| SCHEMBL6408496 | 0.71 | SMYD3 (0.40) | MT-CO2 | |
| SCHEMBL5756198 | 0.70 | KDR (0.61) | F10BDKRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129245-B2 | Anticoagulants which act selectively on factor Xa; fast acting; oral; do not interfere with lysis of blood clots | ELI LILLY AND COMPANY (US) | 2006-10-31 | — | — | US | disclosed |
| US-20050282862-A1 | Aromatic amides | BEIGHT DOUGLAS W | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282862-A1 | Aromatic amides | F11, F12, F5 | F10 12/4885BDKRB1 744/4885LDHA 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.