Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.84 |
| ▸ | CTSL | P07711 | 4/20 | 0.84 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107822 | 0.99 | CTSS (0.85) | CTSSCTSLCTSB | |
| SCHEMBL6108388 | 0.95 | CTSS (0.78) | CTSSCTSL | |
| SCHEMBL14383641 | 0.95 | CTSS (0.78) | CTSSCTSL | |
| SCHEMBL6107584 | 0.94 | CTSS (0.79) | CTSSCTSLCTSB | |
| SCHEMBL6106610 | 0.94 | CTSS (0.79) | CTSSCTSLCTSB | |
| SCHEMBL6106998 | 0.90 | CTSS (0.94) | CTSSCTSLCTSB | |
| SCHEMBL6109403 | 0.89 | CTSS (0.83) | CTSSCTSL | |
| SCHEMBL6110300 | 0.89 | CTSS (0.87) | CTSSCTSLCTSB | |
| SCHEMBL21067516 | 0.89 | CTSS (1.00) | CTSSCTSLCTSB | |
| SCHEMBL6106855 | 0.89 | CTSS (1.00) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982272-B2 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | disclosed |