Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111109 | 1.00 | CNR1 (0.48) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL6109980 | 0.90 | CNR1 (0.52) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL6109976 | 0.90 | CNR1 (0.52) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL6111243 | 0.88 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL6111237 | 0.88 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL1029664 | 0.86 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL5318133 | 0.83 | CNR1 (0.56) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL5318134 | 0.83 | CNR1 (0.56) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL6110408 | 0.80 | PTGS2 (0.44) | CNR1TP53CNR2PTGS2 | |
| SCHEMBL6108855 | 0.80 | PTGS2 (0.44) | CNR1TP53CNR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089378-A1 | Tetrahydro-pyridinyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-04-27 | — | — | US | claimed |
| US-20060089378-A1 | Tetrahydro-pyridinyl pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089378-A1 | Tetrahydro-pyridinyl pyrazole cannabinoid modulators | CNR2, CNR1, GPR18 | CNR1 2/4885KDM4E 1810/4885ALDH1A1 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.