Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106223 | 0.92 | DPP4 (0.41) | DPP4EDNRAALOX5PTGS1PTGS2 | |
| SCHEMBL6107691 | 0.91 | ALOX5 (0.37) | ALOX5PTGS1PTGS2PLA2G2DL3MBTL1 | |
| SCHEMBL6106220 | 0.88 | DPP4 (0.45) | DPP4 | |
| SCHEMBL6108742 | 0.88 | AVPR1B (0.37) | ALOX5PTGS1PTGS2PLA2G2DL3MBTL1 | |
| SCHEMBL6109264 | 0.87 | ALOX5 (0.37) | ALOX5PTGS1PTGS2PLA2G2DL3MBTL1 | |
| SCHEMBL6109274 | 0.87 | DPP4 (0.54) | DPP4 | |
| SCHEMBL6107876 | 0.87 | DPP4 (0.43) | DPP4 | |
| SCHEMBL6107740 | 0.87 | PGR (0.39) | DPP4 | |
| SCHEMBL6110225 | 0.86 | DPP4 (0.57) | DPP4 | |
| SCHEMBL6108201 | 0.85 | DPP4 (0.39) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034039-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |