Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6113157 | 0.95 | KDM4E (0.37) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL1771400 | 0.90 | TUBB4A (0.43) | — | |
| SCHEMBL1771493 | 0.86 | TUBB4A (0.42) | — | |
| SCHEMBL1771491 | 0.86 | TUBB4A (0.42) | — | |
| SCHEMBL6112804 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1 | |
| SCHEMBL6113173 | 0.82 | TUBB4A (0.44) | — | |
| SCHEMBL6113150 | 0.78 | CCNB2 (0.40) | MAPT | |
| SCHEMBL6113102 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1 | |
| SCHEMBL6112766 | 0.76 | CCNB2 (0.47) | MAPT | |
| SCHEMBL22560166 | 0.75 | BRD4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130129-A1 | Efficient Method for Preparing Functionalized Benzosuberenes | BAYLOR UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130129-A1 | Efficient Method for Preparing Functionalized Benzosuberenes | CYP2B6, CYP2A6, GABRA6 | KDM4E 232/4885MEN1 963/4885NPC1 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.