Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188322 | 0.97 | MAPT (0.53) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL8730062 | 0.80 | TDP1 (0.45) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL7098722 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1274675 | 0.78 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL22560178 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL6112770 | 0.78 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL23335828 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL6119284 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL21715395 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHPGDKMT2A | |
| SCHEMBL6113134 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068284-A2 | EFFICIENT METHOD FOR PREPARING FUNCTIONALIZED BENZOSUBERENES | BAYLOR UNIVERSITY (US) | 2012-05-24 | — | — | WO | disclosed |
| US-20120130129-A1 | Efficient Method for Preparing Functionalized Benzosuberenes | BAYLOR UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130129-A1 | Efficient Method for Preparing Functionalized Benzosuberenes | CYP2B6, CYP2A6, GABRA6 | ALDH1A1 1302/4885MAPT 3719/4885CYP1A2 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.