SCHEMBL6114331

SCHEMBL6114331

CC(C)N([SiH3])c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ESR1 P03372 1/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
POLB P06746 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35
PTPN1 P18031 1/20 0.34
CES1 P23141 1/20 0.34
TAAR1 Q96RJ0 2/20 0.34
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MLYCD O95822 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17053464 0.77 TSHR (0.41) ALDH1A1LMNATP53SMN1; SMN2POLB
SCHEMBL8770403 0.74 ALDH1A1 (0.41) ALDH1A1MEN1HTTKMT2APOLB
SCHEMBL236026 0.73 TSHR (0.39) LMNASMN1; SMN2MEN1HTTKMT2A
Isopropyldiphenylamine SCHEMBL2119060 0.72 ALDH1A1 (0.50) ALDH1A1LMNATP53SMN1; SMN2ESR1
SCHEMBL141145 0.72 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2ESR1
Isopropyldiphenylamine SCHEMBL2119054 0.72 ALDH1A1 (0.50) ALDH1A1LMNATP53SMN1; SMN2ESR1
SCHEMBL184934 0.70 ALDH1A1 (0.41) ALDH1A1LMNATP53SMN1; SMN2ESR1
SCHEMBL21158705 0.70 ALDH1A1 (0.41) ALDH1A1LMNATP53SMN1; SMN2ESR1
SCHEMBL94821 0.70 MEN1 (0.44) ALDH1A1LMNATP53SMN1; SMN2ESR1
SCHEMBL28390686 0.70 ALDH1A1 (0.41) ALDH1A1LMNATP53SMN1; SMN2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3535436-B1 PRECURSORS AND FLOWABLE CVD METHODS FOR MAKING LOW-K FILMS TO FILL SURFACE FEATURES VERSUM MAT US LLC (US) 2021-05-12 EP claimed
US-8912353-B2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-12-16 US claimed
EP-2392691-B1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PROD & CHEM (US) 2014-09-03 EP claimed
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-05-24 US claimed
EP-2392691-A1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-07 EP claimed
US-11735413-B2 Precursors and flowable CVD methods for making low-k films to fill surface features VERSUM MATERIALS US, LLC (US) 2023-08-22 US disclosed
EP-3390410-B1 METHODS OF MAKING HIGH PURITY TRISILYLAMINE NATA SEMICONDUCTOR MAT CO LTD (CN) 2022-02-02 EP disclosed
US-11111256-B2 High purity trisilylamine, methods of making, and use JIANGSU NATA OPTO-ELECTRONIC MATERIALS CO. LTD. (CN) 2021-09-07 US disclosed
CN-108602839-B A process for preparing an organoaminosilane; method for producing silylamines from organoaminosilanes 南大光电半导体材料有限公司 2021-06-29 CN disclosed
CN-108602840-B High purity trisilylamine, preparation method and use 南大光电半导体材料有限公司 2021-05-28 CN disclosed
EP-3535436-B1 PRECURSORS AND FLOWABLE CVD METHODS FOR MAKING LOW-K FILMS TO FILL SURFACE FEATURES VERSUM MAT US LLC (US) 2021-05-12 EP disclosed
US-10875877-B2 Method for making an organoaminosilane; a method for making a silylamine from the organoaminosilane DOW SILICONES CORPORATION (US) 2020-12-29 US disclosed
US-8771807-B2 Organoaminosilane precursors and methods for making and using same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-07-08 US disclosed
US-8771807-B2 Organoaminosilane precursors and methods for making and using same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-07-08 US disclosed
US-20130129940-A1 ORGANOAMINOSILANE PRECURSORS AND METHODS FOR MAKING AND USING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-23 US disclosed
US-20130129940-A1 ORGANOAMINOSILANE PRECURSORS AND METHODS FOR MAKING AND USING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-23 US disclosed
US-20130129940-A1 ORGANOAMINOSILANE PRECURSORS AND METHODS FOR MAKING AND USING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-05-23 US disclosed
EP-2535343-A2 Organoaminosilane precursors and methods for making and using same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-12-19 EP disclosed
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-05-24 US disclosed
EP-2392691-A1 Organoaminosilane precursors and methods for depositing films comprising the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128897-A1 Organoaminosilane Precursors and Methods for Depositing Films Comprising Same C1S, C9, C5 ALDH1A1 781/4885LMNA 110/4885TP53 3557/4885
US-20130129940-A1 ORGANOAMINOSILANE PRECURSORS AND METHODS FOR MAKING AND USING SAME AOC1, FUCA1, CD99 ALDH1A1 1005/4885LMNA 2199/4885TP53 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.