SCHEMBL6114451

SCHEMBL6114451

CCCc1ccc2cnccc2c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.51
TBXAS1 P24557 1/20 0.44
HDAC3 O15379 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
PDE10A Q9Y233 1/20 0.41
CYP51A1 Q16850 2/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
PRMT3 O60678 2/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
IMPDH2 P12268 1/20 0.39
BDKRB2 P30411 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31349743 1.00 CYP19A1 (0.51) CYP19A1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL6114835 0.93 CYP19A1 (0.51) CYP19A1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL6115360 0.89 CYP19A1 (0.49) CYP19A1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL6114828 0.88 TDP1 (0.53) CYP19A1TBXAS1BDKRB2
SCHEMBL6114654 0.86 TDP1 (0.51) CYP19A1TBXAS1BDKRB2
SCHEMBL6114395 0.86 TDP1 (0.51) CYP19A1TBXAS1BDKRB2
SCHEMBL6114848 0.86 TDP1 (0.51) CYP19A1TBXAS1BDKRB2
SCHEMBL6115069 0.86 TDP1 (0.51) CYP19A1TBXAS1BDKRB2
SCHEMBL6114695 0.86 TDP1 (0.51) CYP19A1TBXAS1BDKRB2
SCHEMBL6114633 0.86 TDP1 (0.51) CYP19A1TBXAS1BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2821395-A2 Novel disulfonic acid ester as an additive for an electrolyte for a lithium secondary battery Wako Pure Chemical Industries, Ltd. (JP) 2015-01-07 EP disclosed
US-8716513-B2 Process for production of bis-quaternary ammonium salt, and novel intermediate WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-06 US disclosed
EP-2463266-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE Wako Pure Chemical Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20120130107-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130107-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE ASS1, C1S, FHIT CYP19A1 3096/4885TBXAS1 1885/4885HDAC3 1351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.