SCHEMBL6115402

SCHEMBL6115402

CCCCCC[PH](CCCCCC)(CCCCCC)CCCCOC(C)=O.O=S(=O)(NS(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TSHR P16473 2/20 0.41
EPHX1 P07099 2/20 0.41
CES2 O00748 4/20 0.40
NAAA Q02083 1/20 0.37
PLA2G2C Q5R387 1/20 0.37
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FAAH O00519 5/20 0.35
CES1 P23141 1/20 0.35
ACHE P22303 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6115362 0.86 NAAA (0.43) TSHREPHX1CES2NAAARAD52
SCHEMBL6115889 0.86 NAAA (0.43) TSHREPHX1CES2NAAARAD52
SCHEMBL6115342 0.84 EPHX1 (0.55) EPHX1CES2FAAHCES1
SCHEMBL2761162 0.83 ALDH1A1 (0.63) ALDH1A1TSHREPHX1CES2NAAA
SCHEMBL6115273 0.81 EPHX1 (0.40) EPHX1CES2NAAARAD52NPSR1
SCHEMBL6114830 0.80 EPHX1 (0.47) EPHX1CES2FAAHCES1
SCHEMBL29489328 0.78 EPHX1 (0.48) EPHX1CES2FAAHCES1
SCHEMBL6115493 0.77 NAAA (0.47) TSHREPHX1CES2NAAARAD52
SCHEMBL11524782 0.76 ALDH1A1 (0.57) ALDH1A1TSHREPHX1CES2NAAA
SCHEMBL27957447 0.76 ALDH1A1 (0.57) ALDH1A1TSHREPHX1CES2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9555394-B2 Method of making ionic liquid mediated sol-gel sorbents UNIVERSITY OF SOUTH FLORIDA (US) 2017-01-31 US disclosed
US-20140057048-A1 METHOD OF MAKING IONIC LIQUID MEDIATED SOL-GEL SORBENTS UNIVERSITY OF SOUTH FLORIDA (US) 2014-02-27 US disclosed
US-8623279-B2 Ionic liquid mediated sol-gel sorbents UNIVERSITY OF SOUTH FLORIDA (US) 2014-01-07 US disclosed
US-20120128551-A1 IONIC LIQUID MEDIATED SOL-GEL SORBENTS UNIVERSITY OF SOUTH FLORIDA (US) 2012-05-24 US disclosed