Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426995 | 0.79 | KIF11 (0.42) | ALDH1A1KMT2ASNCACES2CES1 | |
| SCHEMBL31276715 | 0.79 | KIF11 (0.42) | ALDH1A1KMT2ASNCACES2CES1 | |
| Water SCHEMBL4365948 | 0.77 | KIF11 (0.41) | ALDH1A1KMT2ASNCACES2CES1 | |
| Water SCHEMBL31276594 | 0.77 | KIF11 (0.41) | ALDH1A1KMT2ASNCACES2CES1 | |
| Water SCHEMBL1427014 | 0.77 | KIF11 (0.41) | ALDH1A1KMT2ASNCACES2CES1 | |
| SCHEMBL3932495 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL30345150 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL11595569 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1HTTHIF1A | |
| SCHEMBL22097317 | 0.75 | MAPT (0.50) | ALDH1A1KMT2AHTTSNCAMAOB | |
| SCHEMBL9448908 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557802-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-15 | — | — | US | disclosed |
| US-8557802-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-15 | — | — | US | disclosed |
| EP-2463279-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20120129832-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20120129832-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129832-A1 | AMIDE DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | ALDH1A1 249/4885KMT2A 747/4885MEN1 3003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.