Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.52 |
| ▸ | CES2 | O00748 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543877 | 0.80 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL10443502 | 0.78 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1165410 | 0.78 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11645892 | 0.76 | CES1 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL732449 | 0.76 | TDP1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL826345 | 0.76 | CA2 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL743301 | 0.76 | CES1 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL125975 | 0.76 | CES1 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL15713087 | 0.76 | CES1 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL14040704 | 0.76 | CES1 (0.57) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | claimed |
| US-4617401-A | ANTISPASMODIC AGENTS, VASODILATORS | SUNTORY LTD. (JP) | 1986-10-14 | — | — | US | claimed |
| JP-6211769-A | — | — | None | — | — | JP | disclosed |
| US-10190009-B2 | Ink composition, ink jet recording method using same, and colored material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20160160065-A1 | INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-06-09 | — | — | US | disclosed |
| EP-3015516-A1 | INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL | Nippon Kayaku Kabushiki Kaisha (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-8802675-B2 | Neuroprotective multifunctional compounds and pharmaceutical compositions comprising them | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (IL) | 2014-08-12 | — | — | US | disclosed |
| US-20120040993-A1 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2012-02-16 | — | — | US | disclosed |
| WO-2010086860-A2 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-08-05 | — | — | WO | disclosed |
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| EP-0265247-B1 | CYCLOPENTYL ETHERS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATION | GLAXO GROUP LIMITED (GB) | 1990-08-08 | — | — | EP | disclosed |
| US-4855293-A | Anti-inflammatory compositions comprising a systemic non-steroidal anti-inflammatory drug and a cyclopentyl ether | GLAXO GROUP LIMITED (GB) | 1989-08-08 | — | — | US | disclosed |
| US-4847369-A | ANTIULCER AGENTS; ANTISECRETORY AGENTS | GLAXO GROUP LIMITED (GB) | 1989-07-11 | — | — | US | disclosed |
| US-4847255-A | Cyclopentyl ethers and their use in medicine | GLAXO GROUP LIMITED (GB) | 1989-07-11 | — | — | US | disclosed |
| US-4824993-A | SYNTHETIC PROSTAGLANDINS, ANTISECRETORY AGENTS | GLAXO GROUP LIMITED (GB) | 1989-04-25 | — | — | US | disclosed |
| EP-0272778-A2 | Cyclopentyl ethers and their use in medicine | GLAXO GROUP LIMITED (GB) | 1988-06-29 | — | — | EP | disclosed |
| EP-0268388-A1 | Anti-inflammatory compositions | GLAXO GROUP LIMITED (GB) | 1988-05-25 | — | — | EP | disclosed |
| EP-0265247-A1 | Cyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1988-04-27 | — | — | EP | disclosed |
| US-4617401-A | ANTISPASMODIC AGENTS, VASODILATORS | SUNTORY LTD. (JP) | 1986-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040993-A1 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | GSR, GRIN1, GRIN2A | CES1 1619/4885CES2 2632/4885TSHR 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.