SCHEMBL125975

SCHEMBL125975

C[N]C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.50
CES2 O00748 6/20 0.50
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 4/20 0.46
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
POLB P06746 2/20 0.46
HSD17B10 Q99714 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
PARP1 P09874 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9000002 0.97 CES1 (0.48) CES1CES2TSHRALDH1A1DAO
SCHEMBL8788839 0.86 SMN1; SMN2 (0.59) ALDH1A1MAPTL3MBTL1KDM4EMEN1
SCHEMBL9126860 0.81 CES2 (0.37) CES1CES2TSHRALDH1A1DAO
SCHEMBL543877 0.78 CES1 (0.55) CES1CES2TSHRALDH1A1DAO
SCHEMBL4269458 0.77 ALDH1A1 (0.56) CES1CES2ALDH1A1TDP1MAPT
SCHEMBL611693 0.76 CES1 (0.52) CES1CES2TSHRALDH1A1DAO
SCHEMBL10443502 0.76 CES1 (0.52) CES1CES2TSHRALDH1A1DAO
SCHEMBL1165410 0.76 CES1 (0.52) CES1CES2TSHRALDH1A1DAO
SCHEMBL3035866 0.75 CES2 (0.50) CES1CES2TSHRALDH1A1DAO
SCHEMBL8995168 0.75 CES2 (0.50) CES1CES2TSHRALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074126-A1 4-METHYLSULFONYLBENZAMIDE COMPOUND, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND USE 江苏中旗科技股份有限公司 2024-04-11 WO claimed
CN-117561242-A 4-methylsulfonyl benzamide compound, preparation method, weeding composition and application 江苏中旗科技股份有限公司 2024-02-13 CN claimed
US-20230183193-A1 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2023-06-15 US claimed
US-20210076680-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-03-18 US claimed
US-10785979-B2 Substituted ketoxime benzoylamides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-29 US claimed
US-10604494-B2 Acylated N-(1 ,2,5-oxadiazol-3-yl)-, N-(1,3,4-oxadiazol-2-yl)-, N-(tetrazol-5-yl)- and N-(triazol-5-yl)-aryl carboxamides, and use thereof as herbicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-03-31 US claimed
US-20200055829-A1 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-02-20 US claimed
US-10556874-B2 N-(1,3,4-oxadiazol-2-yl)aryl carboxamide derivatives with herbicidal action BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-02-11 US claimed
EP-3601242-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES Bayer CropScience Aktiengesellschaft (DE) 2020-02-05 EP claimed
CN-110603250-A Herbicidal 4-difluoromethylbenzamides 拜耳作物科学股份公司 2019-12-20 CN claimed
EP-0042357-B1 AZO DYES, THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1984-06-06 EP claimed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US claimed
EP-0088729-A1 Use of metal complexes of hydrazones as pigments CIBA-GEIGY AG (CH) 1983-09-14 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0055562-A2 Cephalosporin derivatives ICI PHARMA (FR) 1982-07-07 EP claimed
EP-0042357-A2 Azo dyes, their preparation and use CIBA-GEIGY AG (CH) 1981-12-23 EP claimed
US-4271303-A ISOINDOLE DYES FOR POLYESTERS BASF AKTIENGESELLSCHAFT (DE) 1981-06-02 US claimed
US-4153608-A Anthraquinone vat dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1979-05-08 US claimed
US-4072463-A MONOAZO AND DISAZO DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DT) 1978-02-07 US claimed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10604494-B2 Acylated N-(1 ,2,5-oxadiazol-3-yl)-, N-(1,3,4-oxadiazol-2-yl)-, N-(tetrazol-5-yl)- and N-(triazol-5-yl)-aryl carboxamides, and use thereof as herbicides NAT1, AADAC, ACOX3 CES1 1120/4885CES2 498/4885TSHR 1137/4885
US-20200055829-A1 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION DDT, CYP4X1, CBR3 CES1 1402/4885CES2 253/4885TSHR 175/4885
US-10556874-B2 N-(1,3,4-oxadiazol-2-yl)aryl carboxamide derivatives with herbicidal action NOX3, AOX1, NOX1 CES1 611/4885CES2 252/4885TSHR 1564/4885
US-10785979-B2 Substituted ketoxime benzoylamides KYAT3, KMO, OXA1L CES1 808/4885CES2 682/4885TSHR 1846/4885
US-20230183193-A1 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION DDT, CYP4X1, CBR3 CES1 1402/4885CES2 253/4885TSHR 175/4885
US-20210076680-A1 SUBSTITUTED N-(-1,3,4-OXADIAZOLE-2-YL)ARYL CARBOXAMIDES AND THE USE THEREOF AS HERBICIDES DDT, NAT1, AADAC CES1 411/4885CES2 54/4885TSHR 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.