Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119223 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL6119249 | 0.81 | SOS1 (0.40) | KCNK3KCNK9MBOAT4SOS1KDM4E | |
| SCHEMBL6120235 | 0.80 | NOTUM (0.46) | MBOAT4SOS1MRGPRX4KDM4EALDH1A1 | |
| SCHEMBL6120486 | 0.78 | KDM4E (0.41) | SOS1KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL6119323 | 0.75 | CYP4F2 (0.47) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL30694764 | 0.74 | HSD17B10 (0.51) | KCNK3KCNK9MBOAT4SOS1KDM4E | |
| SCHEMBL3943968 | 0.74 | HSD17B10 (0.51) | KCNK3KCNK9MBOAT4SOS1KDM4E | |
| SCHEMBL21817984 | 0.72 | MRGPRX4 (0.51) | MRGPRX4KDM4EGAANOTUMALPL | |
| SCHEMBL24616520 | 0.72 | KDM4E (0.46) | KCNK3KCNK9MBOAT4SOS1KDM4E | |
| SCHEMBL26596781 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |