Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120362 | 0.93 | MAPK8 (0.39) | MAPK8MAPK9MAPK10MAPTALDH1A1 | |
| SCHEMBL6120612 | 0.90 | MAPT (0.38) | APLNRMAPTALDH1A1PTGES2 | |
| SCHEMBL6120931 | 0.87 | BRAF (0.35) | APLNRMAPTLMNAHTTCA12 | |
| SCHEMBL6120692 | 0.84 | TP53 (0.37) | MAPTLMNAACHE | |
| SCHEMBL6121072 | 0.82 | MAPT (0.36) | MAPTALDH1A1ACHE | |
| SCHEMBL6121104 | 0.81 | BRAF (0.34) | ALDH1A1GAALMNAHPGDCA12 | |
| SCHEMBL6120299 | 0.80 | CA12 (0.38) | MAPK8MAPK9MAPK10MAPTALDH1A1 | |
| SCHEMBL6120407 | 0.80 | BRAF (0.33) | MAPK8MAPK9MAPK10 | |
| SCHEMBL6120580 | 0.79 | SLC34A1 (0.32) | ALDH1A1 | |
| SCHEMBL6121078 | 0.77 | PTGES2 (0.35) | APLNRPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |