Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120796 | 0.93 | CSNK1D (0.39) | MMP8MMP12MMP13ACHERAB9A | |
| SCHEMBL6121072 | 0.92 | MAPT (0.36) | MMP8MMP12MMP13ACHERAB9A | |
| SCHEMBL6121218 | 0.92 | MAPT (0.37) | MMP8MMP12MMP13MAPT | |
| SCHEMBL6120362 | 0.91 | MAPK8 (0.39) | ACHERAB9AMAPTCNR1CNR2 | |
| SCHEMBL6121002 | 0.86 | BRAF (0.34) | BRAF | |
| SCHEMBL6120612 | 0.85 | MAPT (0.38) | MMP8MMP12MMP13MAPT | |
| SCHEMBL6120998 | 0.84 | ACLY (0.43) | TP53MAPTBRAFLMNA | |
| SCHEMBL6121996 | 0.84 | JAK2 (0.32) | BRAF | |
| SCHEMBL2994080 | 0.84 | BRAF (0.38) | BRAF | |
| SCHEMBL6120296 | 0.84 | MAPK8 (0.39) | ACHEMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067664-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |