SCHEMBL612202

SCHEMBL612202

C#CC(O)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
KDM4E B2RXH2 2/20 0.39
GMNN O75496 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX1 P07099 3/20 0.36
SHBG P04278 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793827 1.00 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL9063598 1.00 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL9793843 1.00 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL13674295 1.00 TP53 (0.41) TP53KDM4EGMNNLMNAMAPT
SCHEMBL9793964 0.97
SCHEMBL611508 0.97
SCHEMBL5548835 0.92
SCHEMBL7453432 0.86
SCHEMBL131334 0.86
SCHEMBL5188231 0.78 TP53 (0.44) TP53KDM4EGMNNLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058807-A Platinum complex and preparation method and application thereof 广东盛唐新材料技术有限公司 2025-05-30 CN claimed
EP-1140828-B1 3-AZABICYCLO¬3.1.0|HEXANE DERIVATIVES AS OPIATE RECEPTORS LIGANDS PFIZER LTD (GB) 2006-08-09 EP claimed
EP-1077940-B1 4-PHENYLPIPERIDINES FOR THE TREATMENT OF PRURITIC DERMATOSES PFIZER (US) 2004-07-14 EP claimed
CN-120058807-A Platinum complex and preparation method and application thereof 广东盛唐新材料技术有限公司 2025-05-30 CN disclosed
US-11773264-B2 Silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-11773264-B2 Silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-11773264-B2 Silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
CN-116284093-A Alkali promotion system for synthesizing alkenyl borate from propargyl alcohol compound and application of alkali promotion system 河北科技大学 2023-06-23 CN disclosed
CN-111918929-B Silicone composition 信越化学工业株式会社 2022-11-29 CN disclosed
CN-114276247-A 1,5-enyne ester chiral compound and synthesis method thereof 华中师范大学 2022-04-05 CN disclosed
US-20210115252-A1 SILICONE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-04-22 US disclosed
EP-0196617-B1 [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same SYNTEX (U.S.A.) INC. (US) 1989-05-31 EP disclosed
US-4735966-A ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS SYNTEX (U.S.A.) INC. (US) 1988-04-05 US disclosed
EP-0257610-A2 Process and intermediates for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives and for the synthesis of bicyclo(4.2.0)octane derivatives SYNTEX (U.S.A.) INC. (US) 1988-03-02 EP disclosed
EP-0257609-A2 Novel substituted (4.2.0)Bicyclooctane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-03-02 EP disclosed
EP-0255098-A1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-02-03 EP disclosed
US-4678805-A Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1987-07-07 US disclosed
EP-0196617-A1 [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same SYNTEX (U.S.A.) INC. (US) 1986-10-08 EP disclosed
US-4608388-A Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1986-08-26 US disclosed
US-3978100-A Allenic esters, process for preparation thereof and process for rearrangement thereof KURARAY CO., LTD. (JA) 1976-08-31 US disclosed