SCHEMBL612429

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL611924	0.98	MAOA (0.50)	MAOACYP4F2CYP4A11TAAR1DRD2
	SCHEMBL610693	0.98	MAOA (0.50)	MAOACYP4F2CYP4A11TAAR1DRD2
	SCHEMBL613331	0.94	TAAR1 (0.48)	MAOACYP4F2CYP4A11TAAR1DRD2
	SCHEMBL13959790	0.90	TAAR1 (0.48)	MAOACYP4F2CYP4A11TAAR1DRD2
	SCHEMBL238401	0.89	CYP4F2 (0.58)	CYP4F2CYP4A11NOS1CA2CYP2D6
	SCHEMBL27451453	0.88	CYP4F2 (0.50)	MAOACYP4F2CYP4A11TAAR1DRD2
	SCHEMBL2176833	0.87	CYP4F2 (0.56)	CYP4F2CYP4A11NOS1CA2
	SCHEMBL422194	0.87	MAOA (0.58)	MAOATAAR1DRD2DRD1NOS1
	SCHEMBL13959482	0.86	TAAR1 (0.48)	MAOATAAR1DRD2DRD1NOS1
	SCHEMBL611118	0.83	MAOA (0.75)	MAOATAAR1CYP2A6HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.